Psilocybin Laws in New Mexico
New Mexico passed the Medical Psilocybin Act in 2025 and is in Department of Health implementation. The official FAQ says the state is targeting first patient enrollment by the end of December 2026; the program is not open public access yet.
Medical program in buildout, not open retail access
New Mexico's official FAQ says the law passed in the 2025 legislative session, was signed in April 2025, and the Department of Health is targeting first patient enrollment by the end of December 2026. The program page also describes implementation work through December 31, 2027.
DOH rules, advisory-board work, clinician permits, producer and lab standards, patient enrollment dates, and qualifying-condition guidance.
Do not treat New Mexico as Colorado-style personal possession, home cultivation, retail sales, or active public service-center access.
Program home
The Department of Health is building the medical psilocybin program and rulemaking process.
Open official sourceCurrent Legal Status
Medical Program Buildout — Target First Patients Dec. 2026
The Medical Psilocybin Act passed during the 2025 legislative session and was signed by Governor Michelle Lujan Grisham in April 2025. The New Mexico Department of Health is developing rules and says the program goal is enrolling first patients by the end of December 2026. Medical use does not begin until rules are complete and in effect.
Key Legislation
SB 219 / Medical Psilocybin Act (2025) created a regulated medical psilocybin program for qualifying conditions including treatment-resistant depression, PTSD, substance use disorders, and end-of-life care. The law keeps psilocybin federally illegal and does not create Colorado-style personal possession or home cultivation.
Therapeutic Programs
New Mexico's program is in Department of Health rulemaking and implementation as of May 2026. DOH guidance says natural psilocybin from mushrooms is the core program substance and the first-patient enrollment target is the end of December 2026. Verify current DOH rules before relying on any provider claiming active New Mexico access.
Clinical Trials
University of New Mexico Health Sciences Center has participated in psychedelic research. Check ClinicalTrials.gov for Albuquerque and Santa Fe area enrolling psilocybin studies.
Advocacy Organizations
New Mexico Psilocybin Services Coalition, Healing Advocacy Fund, Veterans of War.
Related Resources
People in New Mexico
- Rick Strassman, M.D. — Clinical Psychiatrist; Researcher; Author of DMT: The Spirit Molecule
- Jeffrey Bronfman — Leader, Centro Espírita Beneficente União do Vegetal (UDV) USA; RFRA Plaintiff
Societies & Organizations in New Mexico
- Heffter Research Institute — research
- New Mexico Entheogenic Council — State Policy Advocacy
See how New Mexico compares to neighboring states and find therapy options for residents: